EFEK SAMPING HALOPERIDOL PDF

diltiazem, enalapril, phenytoin, fluconazole, haloperidol, itraconazole, macrolides, nifedipine, quinidine, rapamycin, simvastatin, theophylline, and verapamil. Haloperidol adalah obat yang dikategorikan ke dalam agen antipsikotik, antidiskinetik, Efek samping haloperidol berbeda pada berbagai tingkatan usia . efek. Pada pasien skizofrenia penurunan konsentrasi haloperidol 70 % sehingga efek antipsikosis menurun. Litium dapat meningkatkan efek samping peningkatan.

Author: Dadal Turan
Country: Burundi
Language: English (Spanish)
Genre: Art
Published (Last): 23 July 2017
Pages: 147
PDF File Size: 13.80 Mb
ePub File Size: 11.38 Mb
ISBN: 665-5-11295-938-6
Downloads: 95439
Price: Free* [*Free Regsitration Required]
Uploader: Yozshuktilar

These drugs are metabolized in the liver. Accurate diagnoses and knowledge of the pharmacological properties of the drugs involved allow professionals to tailor their approach to each individual case.

Thrombocyto penia, leukopenia, eosinophilia, hemolytic anemia, agranulocytosis, vasculitis, acute interstitial nephritis, halloperidol septic shock can occur after rifampin administration. This rarely requires that pyrazinamide be discontinued or that the dose be adjusted. Maintain a patent airway by using an oropharyngeal airway or endotracheal tube or, in prolonged cases of coma, by tracheostomy.

The role of chronic hepatitis in isoniazid hepatotoxicity during treatment for latent tuberculosis infection. Comparative efficacy of risperidone versus haloperidol on behavioural and psychological symptoms of dementia Documents.

Haloperidol blocks postsynaptic dopamine D 1 and D 2 receptors in eefek mesolimbic system and decreases the release of hypothalamic and hypophyseal hormones.

It produces calmness and reduces aggressiveness with disappearance of hallucinations and delusions.

A large number of interactions can occur between rifampin and other drugs. The administration of isoniazid in isolation, at doses adjusted to the weight of the patient, rarely produces drug-induced hepatitis, which is practically nonexistent in children but is more common in alcoholic and elderly individuals. Pyrazinamide is bactericidal and has a potent sterilizing effect, principally in the acid medium within macrophages and at sites of acute inflammation.

Haloperidol: Indication, Dosage, Side Effect, Precaution | Indonesia

Use during pregnancy Rifampin is a category C drug. Diminished catalepsy efrk dopamine metabolism distinguish aripiprazole from haloperidol or risperidone Documents. The administration of ethambutol should be avoided in young children, whose visual acuity is difficult to evaluate. It can, however, potentiate the hepatotoxic effect of isoniazid, since rifampin induces hepatic microsomal enzymes of CYP that, in turn, facilitate the conversion of isoniazid into monoacetylhydrazine and hydrazine toxic metabolites of isoniazid.

  ALGEBRA ELENA OTEYZA PDF

Vieira DE, Gomes M. Intramuscular Nausea and vomiting Adult: Forget EJ, Menzies D. The hyperuricemia is typically asymptomatic, and the pain responds well to treatment with aspirin or nonsteroidal anti-inflammatory drugs. Isoniazid administration can also worsen preexisting lupus.

The half-life of isoniazid is approximately 1 h range: Multidrug-resistant and extensively drug-resistant tuberculosis in the West.

A metaanalysis of six studies investigating the use of isoniazid in isolation reported that the incidence of hepatitis was 0. There is controversy as to whether the latter are more likely to develop manifestations of hepatotoxicity than are the former, there being no differences between these phenotypes in terms of antimicrobial activity.

Tuberculosis and diabetes mellitus: The accumulation of pyrazinoic acid decreases the intracellular pH to levels that cause the inactivation of enzymes-such as fatty acid synthase I, which plays a fundamental role in synthesizing fatty acids-and, consequently, the impairment of mycolic acid biosynthesis.

The possibility of interaction between rifampin and other drugs calls for a thorough history taking that focuses on the drugs currently used by patients.

Population of this study was patient ward in Dr. American Academy of Pediatrics Committee on Drugs. Although rifampin is compatible with breastfeeding, the infant should be monitored for jaundice.

Eur J Intern Med. Risperidone compared with haloperidol Documents. Neonates born to mothers who have been under treatment with isoniazid are at risk of developing convulsive seizures. Pyrazinamide crosses the blood-brain barrier, and the concentrations of the drug in the CSF are similar to those in plasma. Effects of Risperidone, Olanzapine, and Haloperidol Documents. Risperidone vs haloperidol on spatial working memory Documents. We briefly review the new guidelines for the pharmacological treatment of tuberculosis, introduced by the Brazilian National Ministry of Health inand describe the general mechanism of action, absorption, metabolization, and excretion of the first-line drugs used in the basic regimen.

  AQAP 2070 PDF

Exanthema can occur due to the use of rifampin or of another drug administered in combination with rifampin. Pyrazinamide is the most hepatotoxic of the drugs cited in the present study. It is supposed that pyrazinamide enters the bacillus passively, is converted into pyrazinoic acid by pyrazinamidase, and reaches high concentrations in the bacterial cytoplasm due to an inefficient efflux system.

Fatal hepatitis is extremely rare and occurs in less than 0.

Perbandingan Risperidone Dengan Haloperidol

May increase risk of arrhythmia when used with drugs that prolong QT interval or diuretics that can cause electrolyte imbalance. Amisulpride superior to haloperidol, risperidone in schizophrenia Documents.

Exacerbation of isoniazid induced peripheral neuropathy by pyridoxine. Isoniazid inhibits the monoamine oxidase enzyme, which is why the drug hhaloperidol not be taken concomitantly with foods rich in tyramine and histamine, such as certain types of cheese Swiss and Cheshirefish tuna and herringand alcohol, especially red wine. Symptoms of overdosage in children include drowsiness, restlessness, confusion, marked extrapyramidal symptoms and hypothermia.

Perbandingan Risperidone Dengan Haloperidol

Ethambutol is widely distributed throughout the body, with the exception of the CSF in patients without meningitis. Risk factors for haloperidlo of isoniazid, rifampin and pyrazinamide in patients hospitalized for pulmonary tuberculosis. However, these reactions are severe and call for a change in the therapeutic regimen. Foods have very little impact on the absorption of pyrazinamide.

Incidence, clinical and epidemiological risk factors, and outcome smaping drug-induced hepatitis due to antituberculous agents in new tuberculosis cases.